Most medications covered on the medical benefit require prior authorization through Specialty Fusion. Click here for a list of the medications authorized by Specialty Fusion*
*Please note: This list is not inclusive of all medications that require prior authorization by Mass General Brigham Health Plan. This list is specific to medical specialty medications that require authorization through Specialty Fusion only.
Online: Access the Specialty Fusion online prior authorization tool through the Provider portal
Phone: 877-519-1908 | Fax: 855-540-3693
MassHealth Prior Authorization Form | Standard Prior Authorization Form
Check the top of the criteria document for additional information, including program details, benefit designation, and contact information.
Providers who are outside of the MGB ACO network can submit requests online through the online authorization submission form.
For non-specialty medications covered on the pharmacy benefit and non-formulary medications, please submit prior authorizations to Optum Rx using the information below.
For specialty medications, please submit prior authorizations to Specialty Fusion using the information below.
To find out if a medication requires prior authorization or if it is listed on the MassHealth formulary please search the MassHealth Drug List.
Specialty medications are required to be filled through a contracted specialty pharmacy after the first fill. To see if a medication is specialty view the Specialty Pharmacy Drug List.
Phone: 877-519-1908 | Fax: 855-540-3693
MassHealth Prior Authorization Form | Standard Prior Authorization Form
Check the top of the criteria document for additional information, including program details, benefit designation, and contact information.
Phone: 800-711-4555 | Fax: 844-403-1029
MassHealth Prior Authorization Form | Standard Prior Authorization Form
Check the top of the criteria document for additional information, including program details, benefit designation, and contact information.
Please note, the following policies are pharmacy benefit drugs that are not aligned with MassHealth. If a policy is not listed below search the MassHealth Drug List for criteria.
Massachusetts Step Therapy Protocol Exception
Off-Label/Non-FDA Approved Indications
Adzynma (ADAMTS13, recombinant-krhn)
Alyglo (immune globulin intravenous, human-stwk)
Anktiva (nogapendekin alfa inbakicept-pmln)
Asceniv (immune globulin IV, human-slra)
Asparlas (calaspargase pegol-mknl)
Aveed (testosterone undecanoate injectable)
Berinert (c1 esterase inhibitor)
Besponsa (inotuzumab ozogamicin)
Bivigam (immune globulin IV, human)
Blenrep (belantamab mafodotin-blmf)
Cinryze (c1 esterase inhibitor)
Cutaquig (immune globulin subcutaneous injection, human-hipp)
Cuvitru (immune globulin subcutaneous injection, human)
Darzalex Faspro (daratumumab-hyaluronidase-fihi)
Datroway (datopotamab deruxtecan-dlnk)
Daxxify (daxibotulinumtoxinA-lanm)
Elahere (mirvetuximab soravtansine-gynx)
Elfabrio (pegunigalsidase alfa-iwxj)
Enhertu (fam-trastuzumab deruxtecan-nxki)
Nexviazyme (avalglucosidase alfa-ngpt)
Ocrevus Zunovo (ocrelizumab hyaluronidase-ocsq)
Octagam (immune globulin IV, human)
Off-Label/Non-FDA Approved Indications
Opdivo Qvantig (nivolumab-hyaluronidase-nvhy)
Opdualag (nivolumab and relatlimab-rmbw)
Otulfi (ustekinumab-aauz vial)
Padcev (enfortumab vedotin-ejfv)
Panzyga (immune globulin IV, human-ifas)
Phesgo (pertuzumab/trastuzumab/hyaluronidase-zzxf)
Polivy (polatuzumab vedotin-piiq)
Pombiliti (cipaglucosidase alfa-atga)
Poteligeo (mogamulizumab-kpkc)
Privigen (immune globulin IV, human)
Pyzchiva (ustekinumab-ttwe vial)
Radicava (edaravone injection)
Rebyota (fecal microbiota, live-jslm)
Remodulin (treprostinil injection)
Rituxan (rituximab) & Rituxan Hycela (rituximab and hyaluronidase)
Ruconest (c1 esterase inhibitor)
Ryplazim (plasminogen, human-tvmh)
Rystiggo (rozanolixizumab-noli)
Selarsdi (ustekinumab-aekn vial)
Simponi Aria (golimumab for infusion)
Skyrizi IV (risankizumab-rzaa)
Stelara (ustekinumab 130 mg/26 mL vial)
Step Therapy Protocol Exception
Steqeyma (ustekinumab-stba vial)
Tecentriq Hybreza (atezolizumab-hyaluronidase-tqjs)
Tivdak (tisotumab vedotin-tftv)
Triferic (ferric pyrophosphate citrate)
Trodelvy (sacituzumab govitecan-hziy)
Tyenne IV (tocilizumab-aazg vial)
Vyvgart (efgartigimod alfa-fcab)
Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase-qvfc)
Vyxeos (daunorubicine/cytarabine)
Wezlana (ustekinumab-auub 130 mg/26 mL vial)
Xembify (immune globulin subcutaneous injection, human-klhw)
Xenpozyme (olipudase alfa-rpcp)
Yesintek (ustekinumab-kfce 130 mg/26 mL vial)
Zilretta (triamcinolone extended-release)
Call provider services at 855-444-4647.