MassHealth medical specialty and pharmacy policies
Prior authorization information
Medications obtained through the medical benefit
Most medications covered on the medical benefit require prior authorization through Specialty Fusion. Click here for a list of the medications authorized by Specialty Fusion*
Helpful information
- Read our authorization process for off label medical specialty medication requests.
- For specialty new-to-market, request authorization through Specialty Fusion. Reference the new-to-market drug policy below for more information.
- For providers outside of the MGB ACO network, Specialty Fusion will review the medical necessity of the medication. Authorization for the member to go outside of the network must be submitted separately to the plan.
*Please note: This list is not inclusive of all medications that require prior authorization by Mass General Brigham Health Plan. This list is specific to medical specialty medications that require authorization through Specialty Fusion only.
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How to submit authorizations to Specialty Fusion
Online: Access the Specialty Fusion online prior authorization tool through the Provider portal
MassHealth Prior Authorization Form | Standard Prior Authorization Form
Phone: 877-519-1908 | Fax: 855-540-3693Check the top of the criteria document for additional information, including program details, benefit designation, and contact information.
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How to submit authorizations to Mass General Brigham Health
Providers who are outside of the MGB ACO network can submit requests online through the online authorization submission form.
Medications obtained through the pharmacy benefit
For non-specialty medications covered on the pharmacy benefit and non-formulary medications, please submit prior authorizations to Optum Rx using the information below.
For specialty medications, please submit prior authorizations to Specialty Fusion using the information below.
To find out if a medication requires prior authorization or if it is listed on the MassHealth formulary please search the MassHealth Drug List.
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Specialty medications
Specialty medications are required to be filled through a contracted specialty pharmacy after the first fill. To see if a medication is specialty view the Specialty Pharmacy Drug List.
Phone: 877-519-1908 | Fax: 855-540-3693
MassHealth Prior Authorization Form | Standard Prior Authorization Form
Check the top of the criteria document for additional information, including program details, benefit designation, and contact information.
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Non-specialty and non-formulary medications
Phone: 800-711-4555 | Fax: 844-403-1029
MassHealth Prior Authorization Form | Standard Prior Authorization Form
Check the top of the criteria document for additional information, including program details, benefit designation, and contact information.
Pharmacy policies
Please note, the following policies are pharmacy benefit drugs that are not aligned with MassHealth. If a policy is not listed below search the MassHealth Drug List for criteria.
Massachusetts Step Therapy Protocol Exception
Medical specialty and dual benefit drug policies
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A - E
Adzynma (ADAMTS13, recombinant-krhn)
Alyglo (immune globulin intravenous, human-stwk)
Asceniv (immune globulin IV, human-slra)
Aveed (testosterone undecanoate injectable)
Berinert (c1 esterase inhibitor)
Besponsa (inotuzumab ozogamicin)
Bivigam (immune globulin IV, human)
Blenrep (belantamab mafodotin-blmf)
Cinryze (c1 esterase inhibitor)
Cutaquig (immune globulin subcutaneous injection, human-hipp)
Cuvitru (immune globulin subcutaneous injection, human)
Daxxify (daxibotulinumtoxinA-lanm)
Elahere (mirvetuximab soravtansine-gynx)
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F - M
Flebogamma (immune globulin IV, human)
Gamastan S/D (immune globulin IM, human)
Gammagard (immune globulin injection, human) (IgA~37μg/mL)
Gammagard S/D (immune globulin IV, human) (IgA<1 μg/mL)
Gammaked (immune globulin injection, human)
Gammaplex (immune globulin IV, human)
Gamunex-C (immune globulin injection, human)
Haegarda (c1 esterase inhibitor)
Hepzato (melphalan hepatic delivery system)
Herceptin Hylecta (trastuzumab-hyaluronidase-oysk)
Hizentra (immune globulin subcutaneous injection, human)
Hyqvia (immune globulin subcutaneous injection, human/hyaluronidase human recombinant)
Idose TR (travoprost intracameral implant)
Imlygic (talimogene laherparepvec)
Injectafer (ferric carboxymaltose injection)
Marqibo (vincristine liposome)
Mepsevii (vestronidase alfa-vjbk)
Monoferric (ferric derisomaltose)
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N - Z
Nexviazyme (avalglucosidase alfa-ngpt)
Octagam (immune globulin IV, human)
Off-Label/Non-FDA Approved Indications
Opdualag (nivolumab and relatlimab-rmbw)
Panzyga (immune globulin IV, human-ifas)
Phesgo (pertuzumab/trastuzumab/hyaluronidase-zzxf)
Polivy (polatuzumab vedotin-piiq)
Pombiliti (cipaglucosidase alfa-atga)
Poteligeo (mogamulizumab-kpkc)
Privigen (immune globulin IV, human)
Radicava (edaravone injection)
Rebyota (fecal microbiota, live-jslm)
Remodulin (treprostinil injection)
Rituxan (rituximab) & Rituxan Hycela (rituximab and hyaluronidase)
Ruconest (c1 esterase inhibitor)
Ryplazim (plasminogen, human-tvmh)
Rystiggo (rozanolixizumab-noli)
Simponi Aria (golimumab for infusion)
Skyrizi IV (risankizumab-rzaa)
Step Therapy Protocol Exception
Trodelvy (sacituzumab govitecan-hziy)
Vyvgart (efgartigimod alfa-fcab)
Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase-qvfc)
Vyxeos (daunorubicine/cytarabine)
Xembify (immune globulin subcutaneous injection, human-klhw)
Xenpozyme (olipudase alfa-rpcp)
Zilretta (triamcinolone extended-release)